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Bio-Medical Signal & System Analysis Lab.

Research

Research Area

  • Multimodal Brain Imaging & Connectomics
  • Brain-Computer/Machine & Human-Computer Interface
  • Biomedical Signal & Image Processing
  • Artificial Intelligence for Biomedical Science
  • Neuroengineering, Neuromodulation & Rehabilitation
  • Clinical, Translational & Systems Neuroscience
  • Biomedical Instrumentation & Healthcare System

Artificial Intelligence (AI) in medicine

Diagnosis of Brain Disorders using Machine Learning

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  • Feature extraction from brain imaging data
  • AI-based automatic diagnosis of brain diseases

Diagnosis of Retina Disease / Rectal Cancer using Deep Learning

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  • Automatic retinal vessel segmentation in fundus images via convolutional neural network
  • Automatic discrimination of rectal cancers using deep convolutional neural network

AI-based Seizure Prediction / Sleep Staging

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  • EEG-based prediction of epileptic seizures
  • Automatic sleep staging & sleep disorder diagnosis from biomedical signals

Brain Research

Brain mapping and Connectomics

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  • Human brain mapping using fMRI, DTI
  • Functional connectivity analysis using brain signals

Brain computer interface (BCI) & EEG Source imaging

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  • Brain computer interfaces using EEG
  • EEG analysis, classification, and source localization

Non-invasive Intracranial Pressure (ICP) Estimation

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  • Brain hemo-&hydro-dynamics modeling
  • Nonlinear state estimation algorithm (e.g.unscented Kalman filter)

Healthcare and Rehabilitation

Healthcare using wearable device (smart-band, driver’s health status monitoring)

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  • Robust heart rate estimation algorithm
  • Nonlinear state estimation algorithm (e.g.unscented Kalman filter)
  • Blood pressure, heart rate, respiration rate, fatigue position, etc.

Biomedical Signal Processing

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  • Motion artifact reduction (adaptive noise cancellation, adaptive comb filtering)
  • Heart and respiratory rates estimation, fetal heart rate detection
  • Compressed covariance sensing
  • Sub-Nyquist sampling

3D Printer / Artificial arm / Exoskeleton

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  • Development of 3D printed exoskeletons for rehabilitation
  • Controlling hand orthosis and prosthesis using EMG signal
  • EEG-based brain machine interface

Neuroscience

Optogenetics & Clarity

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  • Optogenetic stimulation on Alzheimer dementia (AD)
  • Find the mechanism of neurodegenerative change
  • Find novel target for AD treatment

Multielectrode Array (MEA)

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  • 32ch Electroencephalogram (EEG) acquisition
  • 32ch Electrocorticography (ECoG) acquisitio

Translational Neuroscience

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  • Animal stereotaxic surgery
  • Electroencephalogram (EEG) acquisition
  • Neuromodulation (tDCS, optogenetics, etc.)
  • Animal models for diseases (Delirium, Dementia, Epilepsy, etc.)
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